In a recent study, interleukin-17 (IL-17), a T-cell derived cytokine, was the main predictor of microvascular function and arterial compliance, and the authors suggested that this cytokine may play a significant role in the development of endothelial dysfunction and CVD in RA and, also in pro-thrombotic phenotype, in human endothelial cells [49], [50]. Here, IL17A is linked to endothelial dysfunction.