SLC11A1 and infection: The outcome of murine VL infection has a clear genetic basis; genetically resistant mouse (e.g., CBA) has functional Slc11a1 gene that encodes a phagosomal component, solute carrier 11a1 also know as Nramp1, a proton/bivalent cation antiporter that localizes to late endosomes/lysosomes and confers the ability to control the early infection (Crocker et al., 1984; Blackwell et al., 1989).