PIM1 may be important for prostate cancer, in particular because altered levels of PIM1 were observed in a study comparing malignant-to-benign prostate specimens by gene expression microarray and clinically stratified prostate cancer specimens by protein arrays [15], as well as in studies comparing malignant-to-benign prostate specimens and studies of prostate cancer tissue and cell lines using immuno-histochemistry with antibody to PIM1 [11]. Here, PIM1 is linked to Familial prostate cancer.