RAB14 and malaria: When we silenced Rab14 by siRNA, we observed an increase in the percentage of parasites internalized by macrophages, while no difference in phagocytosis was observed with E. coli. As predicted, the overexpression of Rab14 in macrophages induced a decrease in the phagocytosis of P. berghei, while no effect was observed with E. coli. Therefore, these results suggest a crucial role for Rab14, as a negative regulator, in the phagocytosis of the malaria parasite.