IL27 and coronary artery disorder: We have demonstrated that (1) the circulating levels of IL-27 are elevated in patients with CAD, particularly in ACS, and correlated with ox-LDL and Gensini score; (2) IL-27 can be secreted from human monocyte-derived DCs in response to in vitro stimulation with ox-LDL, indicating an important role for IL-27 in the pathogenesis of atherosclerosis.