WFDC2 and endometriosis: In women with endometriosis HE4 levels increased in advanced clinical stage: ASRM stage I (n = 21): median 40 pM (range 29–69), ASRM stage II (n = 15): median 56 pM (range 29–75), ARSM stage III and IV (n = 3): median 73 pM (range 43–122, p < 0.003).