As shown in Figure 2A, the frequencies of apoptotic CD4+ (%, 29.60±12.58) and CD8+ (43.87±24.97) T cells within each T cell subset were significantly increased during acute phase of infection when compared with healthy controls (CD4+, 15.23±4.39; CD8+, 15.32±4.68). This evidence concerns the gene CD4 and infection.