In addition, we demonstrated that CXCL9 and CXCL10 suppressed the fibrosis associated gene expression in liver non-parenchymal cells and primary HSCs of mice in schistosomiasis and TGF-β -activated human hepatic stellate cells LX-2, suggesting their potential anti-fibrosis role in liver fibrosis. The gene discussed is CXCL10; the disease is schistosomiasis.