Positivity for CK7 in more then 75% of cells is regularly observed in several types of carcinoma (www.proteinatlas.org), as well as mesotheliomas [63], but to our knowledge there has not been reported such a degree of augmentation of immunoreactivity for cytokeratins in the course of therapy resistance in carcinomas, nor in mesothelioma. This evidence concerns the gene KRT7 and carcinoma.