TGFB1 and lung disorder: Although SDC-1 and -4 have been implicated in fibrosis [39], [40], [41], [42], [43] and have been suggested as targets for the treatment of lung diseases [44], we did not detect an increase of SDC-1, 3, or 4 in primary human fibroblasts in response to TGFβ or IGFBP-3.