ETS2 and non-small cell lung carcinoma: Although a study identified that Ets-1 and Ets-2 can regulate the expression of microRNA-126 by targeting an Ets binding element in genomic regions upstream of the microRNA-126 and EGFL7 gene in endothelial cells [39], further studies are necessary to determine whether the above mechanism involves in the down-regulation of microRNA-126 in NSCLC.