The expression levels of PIK3R2 and Akt phosphorylation in tumor tissues inversely correlated with the microRNA-126 expression levels (PIK3R2, Spearman r = −0.276, P<0.0001, Akt, Spearman r = −0.164, P = 0.0013, Figure 2D&E and Table 1). This evidence concerns the gene PIK3R2 and neoplasm.