At logistic regression analysis (Table 5), low adiponectin levels were associated with NAFLD diagnosis, younger age, male sex, higher BMI, ADIPOQ genotype, and PNPLA3 148 M alleles (OR 1.67, 95% c.i. 1.07-2.64 for each 148 M allele carried). The gene discussed is PNPLA3; the disease is metabolic dysfunction-associated steatotic liver disease.