Furthermore, numerous C9orf72-negative, TDP-43-negative, p62-positive neuronal cytoplasmic and nuclear inclusions are accumulated in the cerebellar granular cell layer and the dentate gyrus of the hippocampus of the brains of FTD/ALS patients with C9orf72 mutations [8,20]. The gene discussed is SQSTM1; the disease is frontotemporal dementia.