GLUT4 expression (Figure 4) was lower in heart (panel A), gastrocnemius (Panel B) and white adipose tissue (Panel C) at all ages in the MetS group, as compared to C and H. The reduction of GLUT4 in the heart of MetS rats was 54%, 50% and 57% at 3, 6 and 9 months of age, respectively, as compared to C group. The gene discussed is SLC2A4; the disease is metabolic syndrome.