In univariate analysis, lymph node metastasis (P = 0.0039), NCCN criteria (P = 0.0339), postoperative CA19-9 level (P = 0.0082), and Nm23/NDPK-A expression (P = 0.0103) were significantly associated with worse OS (Table 4). This evidence concerns the gene NME1 and metastatic malignant neoplasm in the lymph nodes.