With the multivariate Cox regression model, lymph node metastasis (Hazard Ratio [HR] 2.20, 95% Confidence Interval [CI] 1.33-3.80, P = 0.0020), postoperative CA19-9 level (HR 1.92, 95% CI 1.21-3.04, P = 0.0062), and Nm23/NDPK-A expression (HR 1.97, 95% CI 1.16-3.56, P = 0.0110) remained independent factors predicting poor survival (Table 4). The gene discussed is NME1; the disease is metastatic malignant neoplasm in the lymph nodes.