IL1B and cryopyrin-associated periodic syndrome: As neutrophilic skin inflammation is a prominent feature of cryopyrin-associated inflammatory syndrome (CAPS), which are autoinflammatory disorders, associated with inflammasome hyperactivity and increased IL-1β processing, it is tempting to speculate that Vγ9Vδ2+ T cells may play a role in mediating these events (Kolivras et al., 2011).