More than 10 different genes have been implicated in ALS, including superoxide dismutase 1 (SOD1, ALS1), transactive response DNA-binding protein-43 (TDP-43, ALS10), fused sarcoma (FUS, ALS6), and vamp-associated protein B/C (VAPB, ALS8) [107–111]. Here, TARDBP is linked to amyotrophic lateral sclerosis.