INS and stroke disorder: Secretagogin has received considerable attention due to its significance in insulin secretion from pancreatic beta cells and as a potential biomarker for the diagnosis of stroke and distinct tumors of endocrine origin such as adenocarcinomas of the stomach, pancreas, prostate, colorectum, kidney, and lung small cell carcinoma in the blood of patients (Gartner et al., 2001; Lai et al., 2006; Adolf et al., 2007; Ilhan et al., 2011; Zurek and Fedora, 2012).