The human miR-33b gene is located in intron 17 of the sterol regulatory element binding transcription factor 1 (SREBF1) gene at the genomic locus 17p11.2, which is frequently lost in medulloblastoma (Aldosari et al, 2000; Frühwald et al, 2001; Seranski et al, 1999). Here, SREBF1 is linked to medulloblastoma.