Cluster 2 contained 143 genes and the top biological functions represented were “Infectious disease” (26 genes, p = 1.24E−04−2.55E−02), “Inflammatory response” (23 genes, p = 2.37E−04−2.12E−02) and “Respiratory disease” (13 genes, p = 8.45E−04−2E−02), with the top canonical pathways being “Calcium signalling”, “Gonadotrophin releasing hormone (GNRH) signalling”, “Integrin signalling” and “Tight junction signalling” (Table 3). This evidence concerns the gene GNRH1 and respiratory system disorder.