CCR3 and respiratory system disorder: Cluster 1 consisted of 257 genes and biological functions associated with these included “Infectious disease” (35 genes, p = 1.68E−08−1.17E−02), “Respiratory disease” (26 genes, p = 1.68E−08−1.45E−02) and “Inflammatory response” (37 genes, p = 4.86E−06−2.33E−02), whilst the top canonical pathways represented were “Chemokine signalling”, “G-protein coupled receptor signalling” and “CCR3 signalling in eosinophils” (Table 3).