The proportion of human CD4+ and CD8+ T cells among the CD45+/CD3+-gated subsets of PBMCs from HIV-1-infected hNOK/B51Tg and hNOK mice was analyzed every 2 weeks post-infection by using flow cytometry and compared with that among PBMCs from uninfected hNOK/B51Tg and hNOK mice. The gene discussed is CD8A; the disease is infection.