Based on the expression pattern of these molecules, we analyzed the frequency of human CD8+ T cells expressing CX3CR1 and/or CXCR1 from the spleens of HIV-1-infected and uninfected hNOK/B51Tg mice and of HIV-1-infected and uninfected hNOK mice at 6 weeks post-infection. Here, CXCR1 is linked to infection.