CLC and asthma: This glycan binding protein characteristically forms bi-pyramidal hexagonal crystals, known as the Charcot-Leyden crystals, which have long-been linked with eosinophilic inflammation [17], [19] Though the function of galectin-10 remains largely unknown, several studies have clearly demonstrated its association with eosinophilic inflammatory diseases such as asthma and allergic rhinitis [20], [21], [22], [23], [24].