Our in silico analysis also found that the miR-30b could potentially target genes such as integrin beta 3 (ITGB3), C-reactive protein (CRP), paraoxonase 2 (PON2), retinoblastoma 1(RB1), retinitis pigmenstosa (RP) GTPase regulator (RPGR), and endothelin receptors (EDNR) that are likely candidates of oxidative stress-mediated ocular diseases such as AMD, diabetic retinopathy (DR), glaucoma, RP, and retinoblastoma. The gene discussed is RB1; the disease is age-related macular degeneration.