With respect to BC, models of p53 inactivation via the expression of the SV40 large T-antigen (C3(1)Tag and WAP-TNP8 models) [20], [23], and the p53fl/fl;MMTV-cre transplant model [23], were among the most similar (highlighted in red, Fig. 1A). This evidence concerns the gene TP53 and breast cancer.