We found that even though the splenocytic proliferation with Con A and LPS stimulation was not significantly altered by parenteral feeding, sub-acute peritonitis, or parenteral L-NAME administration, the production of Th1 cytokines, i.e., IFN-γ and IL-2, by T-splenocytes was significantly increased in rats infused with L-NAME compared to those without L-NAME (Figure 4). Here, IL2 is linked to peritonitis.