MT-ND6 and Leber hereditary optic neuropathy: A different nucleotide change affecting the same position m.14482C>G/MT-ND6 has been previously reported [9] in an unrelated family of Turkish ancestry, which noticeably belonged to the haplogroup I. It is conceivable that haplogroup I potentially plays a role similar to J. Furthermore, a third patient carrying the m.14482C>A mutation has been reported by screening a large cohort of patients with optic atrophy from France [43].