SNPs in NRAMP1 were associated with an increased risk of PTB in Gambians [39] but were found to have a protective effect in Cambodians [40], polymorphisms in MBL were associated with protection against TB in South Africans [41] but in South Indians increased susceptibility to this disease [42], while SNPs in VDR were found to increase susceptibility to PTB in three African countries [36] but to have no effect in Cambodians [40]. The gene discussed is SLC11A1; the disease is tuberculosis.