IL1RL1 and systemic lupus erythematosus: Levels of soluble ST2 increase in inflammatory conditions such as systemic lupus erythematosus (SLE), RA (Xu et al., 2008), idiopathic pulmonary fibrosis (Tajima et al., 2003), asthma (Oshikawa et al., 2001), progressive systemic sclerosis, Behcet’s disease, Wegener’s granulomatosis, severe trauma, and sepsis (Akdis et al., 2011).