IL18 and atopic eczema: IL-18 has been associated with autoimmune diseases or inflammatory disorders, bronchial asthma (Harada et al., 2009), atopic dermatitis (Konishi et al., 2002), RA (Gracie et al., 1999; Plater-Zyberk et al., 2001), psoriasis (Ohta et al., 2001), multiple sclerosis (Karni et al., 2002), and type I diabetes (Altinova et al., 2008; Akdis et al., 2011).