PRNP and clostridium difficile infection: The striking range of conformational stability values of PrPSc found with CDI before or after PK in sCJD patients homozygous for codon 129 plymorphism of the PRNP gene and showing either pure Type 1 or Type 2 WB pattern (Fig. 4A and Fig. 4B) by far exceeds the variability expected from the sampling or method itself [4].