Ten per cent of all PDAC cases are related to genetic disorders, e.g. BRCA1 and BRCA2 gene mutations, hereditary non-polyposis colorectal cancer (HNPCC, Lynch syndrome) and familial atypical mole-malignant melanoma (FAMMM) [18-20]. Here, BRCA2 is linked to hereditary nonpolyposis colon cancer.