Still, direct stroke area remained significantly larger in TLR2−/− mice when compared with the WT control group (27.99%) (3 days: WT, 57.92 ± 4.98, n = 10; TLR2−/−, 36.47 ± 3.58, n = 10, P = 0.003; 7 days: WT, 39.00 ± 2.78, n = 10; TLR2−/− 51.43 ± 3.47, n = 10, P = 0.012; 14 days: WT, 22.15 ± 0.96, n = 9; TLR2−/− 28.35 ± 2.09, n = 6, P = 0.010). The gene discussed is TLR2; the disease is Stroke.