NOS2 and myocardial infarction: The lack of intensification of iNOS expression in the rat post-MI cardiac tissue by sildenafil does not agree with what was observed in the mouse in this condition and in ischemia reperfusion injury [12,13], and even in other organs [21-23], suggesting that studies on the time course of iNOS blockade or overexpression on the cardioprotective effects of chronic sildenafil in MI are needed to clarify these discrepancies.