However, in contrast to the drug-induced increases in [11C]-AnxA5-ST uptake, the tumor uptake of [18F]-FDG was unchanged at 72 hrs after the doxorubicin treatment, as compared to untreated mice (Fig. 3E) or compared to [11C]-mTrx-GFP-ST (Fig. 3F). Here, ANXA5 is linked to neoplasm.