At the end of experiments, TUNEL-positive tumor cells from PC-3M-luc-CD44-KD (28–35/ hpf) and PC-3M-luc-CD147-KD (30–36/ hpf) xenografts in DTX-treated groups displayed typical apoptotic cell morphology with nuclear chromatin condensation and fragmentation. The gene discussed is CD44; the disease is neoplasm.