INS and diabetes mellitus: While some experts use routine administration of intensive insulin therapy to normalize glucose levels of hyperglycaemic patients in the ICU, others raise serious concerns over the actual definition of the optimal glucose level, the accuracy of measurements, the resources required to attain tight glycaemic control and the impact of tight glycaemic control across the heterogeneous ICU population including patients with diabetes, previously undiagnosed diabetes or stress-induced hyperglycaemia [14-16].