On the other hand, the results of a multi-center, randomized, controlled trial comparing sensor-augmented pump therapy with a regimen of multiple daily insulin injections in adult and pediatric patients with inadequately controlled type 1 diabetes showed that continuous glucose monitoring can be an effective tool for the intensification of glucose control in patients with type 1 diabetes without incurring an increased risk of hypoglycaemia [49]. Here, INS is linked to type 1 diabetes mellitus.