One study has shown its preventive or therapeutic anti-inflammatory potential in a murine model of trinitro-benzene-sulfonic acid (TNBS)-induced colitis, wherein α, β-amyrin was found to be as efficacious as dexamethasone in reversing the macroscopic and microscopic outcomes of TNBS-induced colitis through suppression of inflammatory cytokines and cyclooxygenase-2 levels, and by inhibition of NF-kB activation[11]. Here, NFKB1 is linked to colitis.