EZH2 and esophageal squamous cell carcinoma: To investigate the functional connection between miRNAs (miR-98, miR-101 and miR-214) and EZH2 in the regulation of ESCC metastasis, we further evaluated the migration and invasion capacity of cells cotransfected with these miRNAs and pcDNA-EZH2 (or empty pcDNA) plasmid.