Moreover, CCND1 amplification on 11q13 has been reported to be associated with luminal subtypes [16], and in agreement with this we found that CCND1 and FGFR1 amplification was most frequent in the luminal B subtype whereas CCND1 amplification was absent from all of the basal-like breast cancers. This evidence concerns the gene FGFR1 and breast cancer.