Selected combined or dichotomized effects of the IL12A rs568408 3`UTR G > A, IL12B rs3212227 3’UTR A > C and -1297 T > C (rs360719) IL-18 variants on the development of anti-HBs in HD patients are shown in Tables 4 and 5, respectively. The gene discussed is IL12B; the disease is Huntington disease.