CD8A and infection: Subsequent studies in the Listeria infection model have identified the CD8α+ DC subset as the cells responsible for efficient CD8 T-cell activation (Campisi et al., 2011; Edelson et al., 2011; Mitchell et al., 2011), as well as serving an important role in establishing a productive infection (Edelson et al., 2011; Mitchell et al., 2011; Waite et al., 2011).