For the growth curve (Figure 5e), the Kruskal-Wallis non-parametric test for multiple comparison analysis demonstrated significant reduction in tumour burden in both the treatment groups versus control (Antp-p21/5-fluorouracil/oxaliplatin-treated group p = 0.008, 5-fluorouracil/oxaliplatin-treated group p = 0.043). The gene discussed is CDKN1A; the disease is neoplasm.