IL1B and myeloid leukemia: In the present study, IL-1β-induced G-CSF caused bone marrow cells to differentiate into neutrophils and this effect was reduced by G-CSF neutralizing antibody, while, in another study, cell supernatants from IL-1β-treated FLS increased the proliferation of murine myeloid leukemia NFS-60 cells and this increase was blocked by anti-G-CSF antibody [24].