AK2 and hemophilia: Besides, this method may be used to reveal the molecular mechanism underlying the reciprocal competitive binding of the antibodies, such as AK2, 24G10 and 6B4, to GPIbα [11], [12], [16], and regulating the physiological and pathological processes of thrombosis and Haemophilia [2], [4], and find its application on researches of other various antibodies, molecular basis of ligand-receptor interactions, and theoretically design of biomolecular drugs.