Higher ephrinA5S expression in peritumoral liver tissue, positive HBsAg and higher Alb showed a reduced lethal risk to 0.42×, 0.39× and 0.40×, respectively, whereas, elder age, larger tumor size and higher AFP exhibited 1.44×, 1.75× and 2.37× poor disease-free survival risk, respectively. The gene discussed is AFP; the disease is neoplasm.