SOCS1 and systemic lupus erythematosus: Figure 5D shows that a large part of SLE patients had an inverse correlation between SOCS1 levels and Jak1 (11 out of 15) and STAT2 (9 out of 15) phosphorylation, suggesting that these patients could fall into two distinguishable groups, one of them related to decreased SOCS1. Nevertheless, Pearson’s correlation analysis of the entire SLE group of patients, failed to reveal a statistically significant association (Fig. S5), in spite of an inverse trend.