The normal prostate epithelial cells (PrEC) failed to express detectable levels of Snail, while Snail was readily detectable in the prostate cancer cell lines LNCaP, the LNCaP derivative cell line C4-2, DU145, and not detectable in 22Rv1 cells (Figure 1A, B). The gene discussed is SNAI1; the disease is Familial prostate cancer.