RNPC3 and infection: Human rabies cell culture and nerve tissue vaccines are inactivated and do not replicate in recipients,65 but they induce robust rVNA responses.66,67 Equivocal evidence has been published regarding induction of non-neutralizing RNP antibody after rabies vaccination.59,68,69 It is notable that suckling mouse brain vaccine (SMB) is used in Perú for rabies PreEP and PEP, although PreEP is typically restricted to persons at occupational risk of infection.