Autosomal dominant mutations in surfactant protein C (SFTPC) and in surfactant protein A2 (SFTPA2) have also been indentified in familial IIP patients, but these genes appear to be infrequently mutated in familial and sporadic cohorts [19-21], with the exception of the Dutch cohort reported in 2010 [12]. This evidence concerns the gene SFTPA2 and idiopathic interstitial pneumonia.