The 3′ UTR of the tumor suppressor PTEN, frequently lost in prostate and other cancer types, shares sequence similarity with the lncRNA PTENP1. The homology in 3′ UTR sequences results in common targeting by the same miRNAs, thus PTENP1 can act as a molecular sponge for miRNAs that target PTEN, limiting PTEN repression by miRNAs (Figure 1(c)). Here, PTEN is linked to cancer.