Among these candidate genes, the polymorphisms on TNFα induced protein 3 (TNFAIP3 or A20) interacting protein 1 (TNIP1) have been found to associate with the disease risk of several autoimmune diseases including psoriasis and SLE [8, 9, 11–15]. The gene discussed is TNIP1; the disease is systemic lupus erythematosus.